RNA mystery solved in triple negative breast cancer
Researchers at Thomas Jefferson University have discovered why conventional efforts to block a tiny strand of ribonucleic acid, called microRNA, in triple negative breast cancer cells failed. In a...
View ArticleGene pair plays crucial role in colon cancer, research shows
Colon cancer is one of the leading causes of cancer-related deaths worldwide, and researchers are hard at work to understand the disease's complex molecular underpinnings. In a new study out this month...
View ArticleDiscovery contributes to future treatment of cervical cancer
A team of scientists from Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has uncovered new molecular interactions involved in the development of...
View ArticleResearch reveals promising novel strategy to target cancer-causing protein
A team of scientists, comprising researchers from the Institute of Molecular and Cell Biology (IMCB), a research institute under the Agency for Science, Technology and Research (A*STAR), Singapore, and...
View ArticleImmune suppressor cells identified for advanced prostate cancer
Immune suppressor cells called MDSCs (myeloid-derived suppressor cells) may be important in developing treatments for advanced prostate cancer, according to a study at The University of Texas MD...
View ArticleVitamin A quells severity of preemie GI disease in mice
After observing that some gastrointestinal disease in premature human and mouse infants progresses only when certain immune system white blood cells go into inflammatory overdrive, Johns Hopkins...
View ArticleEpigenetic regulation of metastatic breast cancer progression may guide...
Boston-A gene that plays a role in the development of breast cancer to metastatic disease has been identified which may help to predict disease progression and serve as a target for the development of...
View ArticleHacking the programs of cancer stem cells
All of the cells in a tumor are the offspring of a single, aberrant cell, but they are not all alike. Only a few retain the capacity of the original cell to create an entire tumor. Such cancer stem...
View ArticleA cancer's surprise origins, caught in action
Researchers at Boston Children's Hospital have, for the first time, visualized the origins of cancer from the first affected cell and watched its spread in a live animal. Their work, published in the...
View ArticleNew clues to common and elusive KRAS cancer gene
One of the most common cancer-causing genes has continuously stymied researchers' efforts to develop treatments against it.
View ArticleSome heart drugs and antibiotics show effective in fighting cancer
North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research. These drugs are normally used to treat...
View ArticleScientists show how cancerous cells evade a potent targeted therapy
Imagine developing a drug designed to inhibit a protein that helps cancer cells proliferate and survive only to find that the drug does not perform very well in the clinic. This was the dilemma faced...
View ArticleBrad Pitt's and fruit flies' cowlicks controlled by cancer protein
What does Brad Pitt have in common with a fruit fly? His Hollywood hairstyles cover a prominent cowlick - the swirl of hair that that is caused by a patterning mechanism also active in our two-winged...
View ArticleHow a metabolic pathway promotes breast cancer metastasis
A metabolic pathway that is up-regulated in certain breast cancers promotes the disease's progression by activating a cell signaling protein called Arf6, according to a paper published in the Journal...
View ArticleStudy suggests link between obesity and kidney cancer
Receptors for leptin, a protein hormone, may be associated with tumor recurrence in patients with renal cell carcinoma (RCC), providing further understanding about molecular links between obesity and...
View ArticleBreast cancer tumor-initiating cells use mTOR signaling to recruit suppressor...
Not every breast cancer tumor follows the same path to grow. Some tumors have the assistance of myeloid-derived suppressor cells (MDSCs), a diverse type of immune cell involved in the suppression of...
View ArticleLab cell study shows that HOXA5 protein acts as tumor suppressor in breast...
Many breast cancers are marked by a lack of HOXA5 protein, a gene product known to control cell differentiation and death, and lower levels of the protein correspond to poorer outcomes for patients....
View ArticleStudy finds breast and ovarian cancer may have similar origins
While breast cancer is the most common cause of cancer death in women worldwide, ovarian cancer also is a significant source of mortality as the fifth leading cause of cancer death among women. These...
View ArticleScientists discover mechanism that turns mutant cells into aggressive cancers
Scientists at The Scripps Research Institute (TSRI) have caught a cancer-causing mutation in the act.
View ArticleResearchers ID cancer gene-drug combinations ripe for precision medicine
In an effort to expand the number of cancer gene mutations that can be specifically targeted with personalized therapies, researchers at University of California San Diego School of Medicine and Moores...
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