Breast cancer tumor-initiating cells use mTOR signaling to recruit suppressor cells to promote tumor

Not every breast cancer tumor follows the same path to grow. Some tumors have the assistance of myeloid-derived suppressor cells (MDSCs), a diverse type of immune cell involved in the suppression of the body's response against tumors. How breast cancer cells recruit MDSCs is not completely understood, but in a paper released today in Nature Cell Biology, Baylor College of Medicine researchers report a new mechanism that helps cancer cells engage MDSCs.