Team explores anti-breast cancer properties of soy
A University of Arizona Cancer Center research team is engaged in a series of studies to investigate how genistein, a component of soy foods, might suppress the development of breast cancer.
View ArticleNew toolkit reveals novel cancer genes
A new statistical model has enabled researchers to pinpoint 27 novel genes thought to prevent cancer from forming, in an analysis of over 2000 tumours across 12 human cancer types. The findings could...
View ArticleCancer research – how a traffic jam causes tumor growth
For tissues to cooperate and perform normal functions, cells need to know which way is up. When cells lose track of their orientation, they can start to grow out of control, and develop into cancer....
View ArticleGenes that hold the clues to bladder cancer and its treatment
Scientists have discovered the 'genetic signatures' of the most common form of bladder cancer - and it could open up the possibility of better-targeted treatment, according to research published today...
View ArticleCellular network identified that 'short circuits' the antitumor effect of...
Researchers from The Wistar Institute discovered a novel form of crosstalk among tumor cells and other cell types in the tumor microenvironment, elucidating the mechanism of action of an...
View ArticleScientists develop a sensor for the most important human cancer gene
If it burns in a house smoke detectors alert us hence protecting life. A molecular smoke alert has now been developed by Dresden researchers for the TP53 gene, the most important human cancer gene. The...
View ArticleResearchers discover a new target for 'triple-negative' breast cancer
So-called "triple-negative" breast cancer is a particularly aggressive and difficult-to-treat form. It accounts for only about 10 percent of breast cancer cases, but is responsible for about 25 percent...
View ArticleResearchers unravel novel mechanism by which tumors grow resistant to...
A Ludwig Cancer Research study has uncovered a key mechanism by which tumors develop resistance to radiation therapy and shown how such resistance might be overcome with drugs that are currently under...
View ArticleImportant tumor suppressor discovered in immune cells
A team from Technical University of Munich has discovered an "emergency shut-off switch" in immune system T cells. Their results could lead to new therapies against T cell non-Hodgkin's lymphoma...
View ArticleTime matters: Does our biological clock keep cancer at bay?
Our body has an internal biological or "circadian" clock, which cycles daily and is synchronized with solar time. New research done in mice suggests that it can help suppress cancer. The study,...
View ArticleNovel compound restores immune response in patients with melanoma
A novel compound may restore immune response in patients with melanoma, according to a study presented at the ESMO Immuno Oncology Congress 2017.
View ArticleNew strategy for unleashing cancer-fighting power of p53 gene
Tumor protein p53 is one of the most critical determinants of the fate of cancer cells, as it can determine whether a cell lives or dies in response to stress. In a new study published today in the...
View ArticleResearchers map molecular interaction that prevents aggressive breast cancer
Researchers in Italy have discovered how specific versions of a protein called Numb protect the key tumor suppressor p53 from destruction. The study, which will be published December 21 in the Journal...
View ArticleNew immunotherapy approach boosts body's ability to destroy cancer cells
Few cancer treatments are generating more excitement these days than immunotherapy—drugs based on the principle that the immune system can be harnessed to detect and kill cancer cells, much in the same...
View ArticleCancer's gene-determined 'immune landscape' dictates progression of prostate...
The field of immunotherapy - the harnessing of patients' own immune systems to fend off cancer - is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in...
View ArticleImmunosuppressive cells in newborns play important role in controlling...
New research led by The Wistar Institute, in collaboration with Sun Yat-sen University in China, has characterized the transitory presence of myeloid-derived suppressor cells (MDSCs) in mouse and human...
View ArticleGene duplication explains tumor aggressiveness
Pancreatic cancer is a form of cancer associated with the highest mortality rates in the world. Genetic changes that could explain its aggressiveness and early metastasis are elusive. A team at...
View ArticleStudy shows liver cells with whole genome duplications protect against cancer
Researchers at the Children's Medical Center Research Institute (CRI) at UT Southwestern have discovered that cells in the liver with whole genome duplications, known as polyploid cells, can protect...
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