Tumor protein p53 is one of the most critical determinants of the fate of cancer cells, as it can determine whether a cell lives or dies in response to stress. In a new study published today in the journal Nature Communications, a research team from the Department of Pharmacology and Therapeutics at Roswell Park Cancer Institute reports their discovery of a major mechanism by which cells regulate this important and multifunctional tumor suppressor, opening up new avenues for cancer research and treatment.
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