Duplicating immunity boosting regulatory T-cells to unprecedented levels
University of Minnesota Medical School researchers have discovered a method to quickly and exponentially grow regulatory T-cells – also known as "suppressor cells." The new process enables replication...
View ArticleImmune cells link pregnancy and tumor spread
Individuals with cancer often do not die as a result of their initial tumor but as a result of tumors at distant sites that are derived from the initial tumor. Pregnancy is a condition that seems to be...
View ArticleStudy: Impediment to some cancer immunotherapy involves the free radical...
Researchers at the Moffitt Cancer Center in Tampa, Fla., and colleagues have found that tumor cell resistance to a specific cancer immunotherapy designed to kill cancer cells can be blamed on a...
View ArticleLower antioxidant level might explain higher skin-cancer rate in males
Men are three times more likely than women to develop a common form of skin cancer but medical science doesn't know why. A new study may provide part of the answer.
View ArticleStudy finds potential key to immune suppression in cancer
In a study investigating immune response in cancer, researchers from Moffitt Cancer Center in Tampa, Fla., and the University of South Florida have found that interaction between the immune system's...
View ArticleBone marrow transplantation assists in acceptance of donated organs
In an organ transplant the recipient protects himself with an immune reaction against the alien organ. This reaction is counteracted long-term with the use of immunosuppressants. In future this...
View ArticleStudies show that pancreatic cancer can run but not always hide from the...
A pair of recent studies describes how pancreatic cancer cells produce a protein that attracts the body's immune cells and tricks them into helping cancer cells grow. The research, published by Cell...
View ArticleCold viruses point the way to new cancer therapies
Cold viruses generally get a bad rap—which they've certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a...
View ArticleResearchers say effective immunotherapy for melanoma hinges on blocking...
(Medical Xpress)—Researchers at the Moffitt Cancer Center have found that delayed tumor growth and enhanced survival of mice bearing melanoma were possible by blocking the reconstitution of...
View ArticleProtein that represses critical checkpoint protein for cellular growth helps...
(Medical Xpress)—One of the hallmarks of cancer is unchecked cellular growth. Fortunately, our cells contain a number of tumor suppressor proteins, including the cell cycle regulator p21, to keep cell...
View ArticleResearchers say silencing of retinoblastoma gene regulates differentiation of...
Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer. This...
View ArticleResearchers probe the enigma of healing element that is also the enemy
The same factor in our immune system that is instrumental in enabling us to fight off severe and dangerous inflammatory ailments is also a player in doing the opposite at a later stage, causing the...
View ArticleLiver cancers armed with many strategies for evading immune response
(Medical Xpress)—Researchers at Roswell Park Cancer Institute (RPCI) have published findings that help explain how a common and particularly resilient form of liver cancer evades the body's natural...
View ArticleSome immune cells appear to aid cancer cell growth, study finds
The immune system is normally known for protecting the body from illness. But a subset of immune cells appear to be doing more harm than good.
View ArticleResearch findings reveal that tumors promote myeloid-derived suppressor cell...
(Medical Xpress)—Researchers at Roswell Park Cancer Institute (RPCI) have uncovered a new pathway by which cancer cells, such as in breast cancer, stimulate the expansion of myeloid-derived suppressor...
View ArticleResearchers discover mechanism controlling the development of myelodysplastic
Researchers at the Moffitt Cancer Center have discovered a control mechanism that can trigger the development of myelodysplastic syndromes (MDS), a group of blood cancers. This finding may lead to...
View ArticleDismantling pancreas cancer's armor
Pancreas cancer is notoriously impervious to treatment and resists both chemotherapy and radiotherapy. It has also been thought to provide few targets for immune cells, allowing tumors to grow...
View ArticleScientists discover potential new target for cancer immunotherapy
Scientists have found a way to target elusive cells that suppress immune response, depleting them with peptides that spare other important cells and shrink tumors in preclinical experiments, according...
View ArticleIs the next 'new' cancer drug already in your medicine cabinet?
It turns out that the same types of drugs that help reduce watery eyes and runny noses during allergy season might also help ward off tumors too. A new research report appearing in the July 2014 issue...
View ArticleImmune activity shortly after surgery holds big clue to recovery rate, study...
The millions of people who undergo major surgery each year have no way of knowing how long it will take them to recover from the operation. Some will feel better within days. For others, it will take a...
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